Antimicrobial Screening of Actinobacteria using a Modified Cross-Streak Method

نویسندگان

  • Sonashia Velho-Pereira
  • N M Kamat
چکیده

Out of the 30 actinobacterial cultures screened for antimicrobial activity, 28 cultures were found to produce active products against various pathogenic microorganisms such as Gram-negative, Gram-positive bacteria and yeast, using a modified cross streak method. The modified method helped in easy quantification of results and also in ruling out probable mutual antibiosis. The actinobacterial strains that showed the ability to produce antimicrobial compounds belonged to Streptomyces (53%), Micromonospora (13%) and Actinomadura (10%) genera. Streptomyces sp. strain MMA-5 showed the highest multispecific antibiosis efficiency score value. Broad antibiotic spectrum activity was exhibited by Streptomyces sp. strain MMA-2 and Micromonospora sp. strain MMA-8. The multidrug resistant human pathogenic yeast strain Candida albicans was inhibited by 18 actinobacterial strains.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antimicrobial, Antioxidant and Cytotoxic Activity of Marine Streptomyces MS-60 Isolated from Bay of Bengal

The main aim of the study was to evaluate the antimicrobial, antioxidant and cytotoxic potential of crude extract of Marine Streptomyces species isolated from soil of Chennai coast, Tamilnadu. Primary and Secondary screening for antimicrobial activity was determined by Cross streak method and Agar well diffusion method respectively. Gram positive bacteria were found most sensitive to the actino...

متن کامل

Isolation, Identification and Screening of Saharan Actinomycete Strain Streptomyces fimbriatus AC31 Endowed with Antimicrobial Activity

The increasing global public health concern of antimicrobial resistance (AMR) necessitates exploration of natural antimicrobial agents as potential alternatives. This study aims to investigate antimicrobial activities of Saharan actinomycetes, with specific focus on the strain Streptomyces fimbriatus AC31, that holds promising potential as an alternative to combat AMR. In this context, 32 actin...

متن کامل

Isolation and Characterisation of Actinobacteria from Algerian Sahara Soils with Antimicrobial Activities

Extreme ecosystems can be a source of untapped micro-organisms able to produce novel bioactive compounds of industrial interest. Consequently, in this work, 32 Actinomycetes were isolated from 6 soil samples collected from Algerian Sahara in searching for untapped producers of novel antimicrobial compounds. All the isolates were further subjected to antimicrobial screening against pathogenic ba...

متن کامل

Isolation, Characterization and Antimicrobial Potential of Endophytic Actinomycetes

ISSN: 2319-7706 Volume 5 Number 7 (2016) pp. 100-116 Journal homepage: http://www.ijcmas.com Endophytes are organisms that are intimately associated with various parts of plants. Endophytic actinomycetes represent actinomycetes of various genera that are associated with various parts of the plants. The beneficial interactions of endophytic actinomycetes with plants are being considered as an im...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 73  شماره 

صفحات  -

تاریخ انتشار 2011